(S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase (Q79750026)
scientific article published on 08 February 2007
Language:
Current Data About (S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase
(P31) (Q13442814)
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(P577) Thursday, February 8, 2007
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(P1433) (Q1500272)
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(P1476) "(S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent anti-inflammatory activities by inhibiting the release of IL-1beta and IL-18" (language: en)
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(P2093) Woods Wannamaker
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Robert Davies
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Mark Namchuk
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John Pollard
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Pamella Ford
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George Ku
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Caroline Decker
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Paul Charifson
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Peter Weber
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Ursula A Germann
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Keisuke Kuida
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John C R Randle
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other details
description scientific article published on 08 February 2007

External Links
(P356) 10.1124/JPET.106.111344
(P698) 17289835