Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one (J-113397) (Q28140733)
scientific article (publication date: 16 December 1999)
Language:
Current Data About Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one (J-113397)
(P31) (Q13442814)

(P304) 5061-3

5061-5063
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

(P407) (Q1860)

(P433) 25
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

(P478) 42
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

(P577) Thursday, December 16, 1999

+1999-12-00T00:00:00Z
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

(P921) (Q427523)

(P1433) (Q900316)
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

(P1476) "Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one (J-113397)" (language: en)

"Discovery of the First Potent and Selective Small Molecule Opioid Receptor-like (ORL1) Antagonist:  1-[(3R,4R)-1-Cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl- 1,3-dihydro-2H-benzimidazol-2-one (J-113397)" (language: en)
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

(P2093) H Kawamoto
(P1545) 1

S Ozaki
(P1545) 2

Y Itoh
(P1545) 3

M Miyaji
(P1545) 4

S Arai
(P1545) 5

H Nakashima
(P1545) 6

T Kato
(P1545) 7

H Ohta
(P1545) 8

Y Iwasawa
(P1545) 9

Hiroshi Kawamoto
(P1545) 1
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

Satoshi Ozaki
(P1545) 2
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

Yoshiki Itoh
(P1545) 3
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

Mitsuru Miyaji
(P1545) 4
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

Sachie Arai
(P1545) 5
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

Hiroshi Nakashima
(P1545) 6
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

Tetsuya Kato
(P1545) 7
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

Hisashi Ohta
(P1545) 8
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

Yoshikazu Iwasawa
(P1545) 9
(P248)
(P854) https://doi.org/10.1021%2FJM990517P
(P813) Wednesday, May 24, 2017

other details
aliases Discovery of the First Potent and Selective Small Molecule Opioid Receptor-like (ORL1) Antagonist:  1-[(3R,4R)-1-Cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl- 1,3-dihydro-2H-benzimidazol-2-one (J-113397)
description scientific article (publication date: 16 December 1999)

External Links
(P356) 10.1021/JM990517P
(P698) 10602690