2-isopropylmalate synthase activity (Q21756777)
Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).
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aliases GO:0003852
alpha-IPM synthetase activity
isopropylmalate synthetase activity
isopropylmalate synthase activity
alpha-isopropylmalate synthetase activity
alpha-isopropylmalic synthetase activity
3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity
alpha-isopropylmalate synthase activity
acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
description Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).

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