hydroxymethylglutaryl-CoA synthase activity (Q21118282)
Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).
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aliases (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)
hydroxymethylglutaryl coenzyme A synthase activity
(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity
3-hydroxy-3-methylglutaryl-coenzyme A synthase activity
3-hydroxy-3-methylglutaryl CoA synthetase activity
acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
beta-hydroxy-beta-methylglutaryl-CoA synthase activity
acetoacetyl coenzyme A transacetase activity
hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity
3-hydroxy-3-methylglutaryl coenzyme A synthase activity
HMG-CoA synthase activity
3-hydroxy-3-methylglutaryl coenzyme A synthetase activity
GO:0004421
3-hydroxy-3-methylglutaryl-CoA synthase activity
description Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).

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