I-kappaB kinase/NF-kappaB signaling (Q21095171)
The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subu
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aliases GO:0007249
 I-kappaB kinase/NF-kappaB signal transduction
 canonical NF-kappaB signaling cascade
description The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subu

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(P686) GO:0007249