guanyl-nucleotide exchange factor activity (Q14860383)
Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
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aliases guanyl-nucleotide release factor activity
GDP-dissociation stimulator activity
GDS
guanyl-nucleotide releasing factor
GEF
GO:0005085
description Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.

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